COFFEE - Uses, Side Effects, and More

Ephedrine interacts with COFFEE

Stimulant drugs speed up the nervous system. The caffeine in coffee and ephedrine are both stimulant drugs. Drinking coffee and taking ephedrine might cause too much stimulation and sometimes serious side effects and heart problems. Do not take caffeine-containing products and ephedrine at the same time.

Adenosine (Adenocard) interacts with COFFEE

The caffeine in coffee might block the effects of adenosine. Adenosine is often used by doctors to do a test on the heart. This test is called a cardiac stress test. Stop consuming coffee or other caffeine-containing products at least 24 hours before a cardiac stress test.

Alcohol (Ethanol) interacts with COFFEE

The body breaks down the caffeine in coffee to get rid of it. Alcohol can decrease how quickly the body breaks down caffeine. Taking coffee along with alcohol might cause too much caffeine in the bloodstream and caffeine side effects including jitteriness, headache, and fast heartbeat.

Alendronate (Fosamax) interacts with COFFEE

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Coffee can decrease how much alendronate (Fosamax) the body absorbs. Taking coffee and alendronate (Fosamax) at the same time can decrease the effectiveness of alendronate (Fosamax). Don't drink coffee within two hours of taking alendronate (Fosamax).

Antibiotics (Quinolone antibiotics) interacts with COFFEE

Coffee contains caffeine. The body breaks down caffeine to get rid of it. Some antibiotics might decrease how quickly the body breaks down caffeine. Taking these antibiotics along with coffee might increase the risk of side effects including jitteriness, headache, increased heart rate, and other side effects. Some antibiotics that decrease how quickly the body breaks down caffeine include ciprofloxacin (Cipro), gemifloxacin (Factive), levofloxacin (Levaquin), moxifloxacin (Avelox), and others.

Birth control pills (Contraceptive drugs) interacts with COFFEE

The body breaks down the caffeine in coffee to get rid of it. Birth control pills can decrease how quickly the body breaks down caffeine. Taking coffee along with birth control pills can cause jitteriness, headache, fast heartbeat, and other side effects. Some birth control pills include ethinyl estradiol and levonorgestrel (Triphasil), ethinyl estradiol and norethindrone (Ortho-Novum 1/35, Ortho-Novum 7/7/7), and others.

Clozapine (Clozaril) interacts with COFFEE

The body breaks down clozapine to get rid of it. The caffeine in coffee might decrease how fast the body breaks down clozapine. Taking coffee along with clozapine can increase the effects and side effects of clozapine.

Dipyridamole (Persantine) interacts with COFFEE

The caffeine in coffee might block the effects of dipyridamole. Dipyridamole is often used by doctors to do a test on the heart. This test is called a cardiac stress test. Stop drinking coffee or other caffeine-containing products at least 24 hours before a cardiac stress test.

Disulfiram (Antabuse) interacts with COFFEE

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The body breaks down the caffeine in coffee to get rid of it. Disulfiram can decrease how quickly the body gets rid of caffeine. Taking coffee along with disulfiram might increase the effects and side effects of coffee including jitteriness, hyperactivity, irritability, and others.

Estrogens interacts with COFFEE

The body breaks down the caffeine in coffee to get rid of it. Estrogens can decrease how quickly the body breaks down caffeine. Taking estrogen pills and drinking coffee can cause jitteriness, headache, fast heartbeat, and other side effects. If you take estrogen pills limit your caffeine intake. Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others.

Fluvoxamine (Luvox) interacts with COFFEE

The body breaks down the caffeine in coffee to get rid of it. Fluvoxamine can decrease how quickly the body breaks down caffeine. Taking caffeine along with fluvoxamine might cause too much caffeine in the body, and increase the effects and side effects of caffeine.

Levothyroxine (Synthroid, others) interacts with COFFEE

Drinking some types of coffee might reduce the amount of levothyroxine that is absorbed when taken by mouth. This can decrease how well levothyroxine works. Avoid drinking coffee at the same time that you take levothyroxine and for an hour afterwards.

Lithium interacts with COFFEE

Your body naturally gets rid of lithium. The caffeine in coffee can increase how quickly your body gets rid of lithium. If you take products that contain caffeine and you take lithium, stop taking caffeine products slowly. Stopping caffeine too quickly can increase the side effects of lithium.

Medications for depression (MAOIs) interacts with COFFEE

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The caffeine in coffee can stimulate the body. Some medications used for depression can also stimulate the body. Drinking caffeinated coffee and taking some medications for depression might cause too much stimulation and serious side effects including fast heartbeat, high blood pressure, nervousness, and others. Some of these medications used for depression include phenelzine (Nardil), tranylcypromine (Parnate), and others.

Medications for depression (Tricyclic antidepressants) interacts with COFFEE

Coffee contains chemicals called tannins. Tannins can bind to many medications and decrease how much medicine the body absorbs. To avoid this interaction avoid coffee one hour before and two hours after taking medications for depression called tricyclic antidepressants. Some medications for depression include amitriptyline (Elavil) or imipramine (Tofranil, Janimine).

Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with COFFEE

Coffee might slow blood clotting. Taking coffee along with medications that also slow clotting might increase the chances of bruising and bleeding. Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.

Pentobarbital (Nembutal) interacts with COFFEE

The stimulant effects of the caffeine in coffee can block the sleep-producing effects of pentobarbital.

Phenothiazines interacts with COFFEE

Coffee contains chemicals called tannins. Tannins can bind to many medications and decrease how much medicine the body absorbs. To avoid this interaction, avoid coffee one hour before and two hours after taking phenothiazine medications. Some phenothiazine medications include fluphenazine (Permitil, Prolixin), chlorpromazine (Thorazine), haloperidol (Haldol), prochlorperazine (Compazine), thioridazine (Mellaril), and trifluoperazine (Stelazine).

Phenylpropanolamine interacts with COFFEE

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The caffeine in coffee can stimulate the body. Phenylpropanolamine can also stimulate the body. Taking caffeine and phenylpropanolamine together might cause too much stimulation and increase heartbeat, blood pressure, and cause nervousness.

Riluzole (Rilutek) interacts with COFFEE

The body breaks down riluzole to get rid of it. Drinking coffee can decrease how fast the body breaks down riluzole and increase the effects and side effects of riluzole.

Stimulant drugs interacts with COFFEE

Stimulant drugs speed up the nervous system. By speeding up the nervous system, stimulant medications can make you feel jittery and speed up your heartbeat. The caffeine in coffee can also speed up the nervous system. Drinking coffee along with stimulant drugs might cause serious problems including increased heart rate and high blood pressure. Avoid taking stimulant drugs along with coffee. Some stimulant drugs include diethylpropion (Tenuate), epinephrine, phentermine (Ionamin), pseudoephedrine (Sudafed), and many others.

Theophylline interacts with COFFEE

The caffeine in coffee works similarly to theophylline. Caffeine can also decrease how quickly the body gets rid of theophylline. Drinking coffee and taking theophylline might increase the effects and side effects of theophylline.

Verapamil (Calan, others) interacts with COFFEE

The body breaks down the caffeine in coffee to get rid of it. Verapamil can decrease how quickly the body gets rid of caffeine. Drinking coffee and taking Verapamil can increase the risk of side effects for coffee including jitteriness, headache, and an increased heartbeat.

Medications for asthma (Beta-adrenergic agonists) interacts with COFFEE

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Coffee contains caffeine. Caffeine can stimulate the heart. Some medications for asthma can also stimulate the heart. Taking caffeine with some medications for asthma might cause too much stimulation and cause heart problems. Some medications for asthma include albuterol (Proventil, Ventolin, Volmax), metaproterenol (Alupent), terbutaline (Bricanyl, Brethine), and isoproterenol (Isuprel).

Nicotine interacts with COFFEE

Taking caffeine in coffee along with nicotine might increase rapid heart rate and blood pressure.

Water pills (Diuretic drugs) interacts with COFFEE

The caffeine in coffee can reduce potassium levels. "Water pills" can also decrease potassium levels in the body. Taking caffeine with water pills might cause potassium levels to drop too low. Some "water pills" that can deplete potassium include chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, HydroDiuril, Microzide), and others.

Cimetidine (Tagamet) interacts with COFFEE

The body breaks down the caffeine in coffee to get rid of it. Cimetidine can decrease how quickly your body breaks down caffeine. Taking cimetidine along with coffee might increase the chance of caffeine side effects including jitteriness, headache, fast heartbeat, and others.

Fluconazole (Diflucan) interacts with COFFEE

The body breaks down the caffeine in coffee to get rid of it. Fluconazole might decrease how quickly the body gets rid of caffeine. Taking fluconazole and drinking coffee might increase the effects and side effects of coffee including nervousness, anxiety, and insomnia.

Medications for diabetes (Antidiabetes drugs) interacts with COFFEE

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Coffee might increase blood sugar. Diabetes medications are used to lower blood sugar. By increasing blood sugar, coffee might decrease the effectiveness of diabetes medications. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed. Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.

Mexiletine (Mexitil) interacts with COFFEE

Coffee contains caffeine. The body breaks down caffeine to get rid of it. Mexiletine can decrease how quickly the body breaks down caffeine. Taking Mexiletine along with coffee might increase the caffeine effects and side effects of coffee.

Terbinafine (Lamisil) interacts with COFFEE

The body breaks down the caffeine in coffee to get rid of it. Terbinafine can decrease how fast the body gets rid of caffeine and increase the risk of side effects including jitteriness, headache, increased heartbeat, and other effects.

  • For headache or improving mental alertness: The typical dose of caffeine is up to 250 mg per day, which is about 2 cups of coffee. Even a single cup of coffee with caffeine can be used.
  • For Parkinson disease: 3-4 cups of caffeinated coffee per day or 421 mg to 2716 mg total caffeine. However, a significantly lower risk of developing Parkinson disease has also been associated with as little as 124 mg to 208 mg of caffeine (approximately one to two cups of coffee).
  • For death from any cause: At least one cup of ground, instant, or decaffeinated coffee per day has been used long-term.
  • For diabetes: 900 mg caffeine per day (six or more cups of coffee per day) long-term.
  • Impaired movement of food through the intestines after surgery: 100 mL of coffee three times a day starting after surgery and continuing until the first bowel movement has been used.

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on ishonest. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2018.

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