Niacin Deficiency

niacin-deficiency-symptoms-and-treatments' target='_blank' rel='noopener noreferrer' >Niacin deficiency is a condition that occurs when a person doesn't get enough or can't absorb niacin or its amino acid precursor, tryptophan. In the United States, niacin deficiency is exceedingly rare. However, there have been outbreaks of niacin deficiency in areas of the world where food is scarce.

Also known as vitamin B3 or nicotinic acid, niacin is one of eight B vitamins. Like all B vitamins, niacin plays a role in converting carbohydrates into glucose, metabolizing fats and proteins, and keeping the nervous system working properly. Niacin also helps the body make sex- and stress-related hormones and improves circulation and cholesterol levels.

Tryptophan is one of the amino acids that makes up protein. Your liver can convert tryptophan from high-protein foods like meats and milk into niacin.

Niacin Deficiency Symptoms

Severe deficiency, called pellagra, can cause symptoms related to the skin, digestive system, and nervous system. They include:

• thick, scaly pigmented rash on skin exposed to sunlight
• swollen mouth and bright red tongue
• vomiting and diarrhea
• headache
• apathy
• fatigue
• depression
• disorientation
• memory loss

If not treated, pellagra can lead to death. Pellagra can be reversible with niacin supplementation prescribed under the supervision by your doctor.

Pellagra is rare in the U.S. Most people get the recommended amount of niacin in the foods they eat every day.

Niacin Deficiency Causes

In the 1800s, pellagra was common among poor Americans whose diets consisted mostly of corn, molasses, and salt pork -- all poor sources of niacin. Today, most people in the developed world get plenty of niacin in their diets. Niacin deficiency is more likely to be caused by problems that affect absorption of niacin or tryptophan. The most common cause is alcoholism. Other possible causes include disorders of the digestive system and prolonged treatment with the tuberculosis drug isoniazid (Laniazid, Nydrazid).

Niacin Deficiency Treatments

The recommended daily allowance (RDA) for niacin is 16 milligrams per day for men and 14 milligrams per day for women. Good sources of niacin include red meat, fish, poultry, fortified breads and cereals, and enriched pasta and peanuts.

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