GRAPE - Uses, Side Effects, and More

Phenacetin interacts with GRAPE

Drinking grape juice might increase how quickly the body breaks down phenacetin. Taking phenacetin along with grape juice might decrease the effects of phenacetin.

Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with GRAPE

Grape extract might slow blood clotting. Taking grape extract along with medications that also slow blood clotting might increase the risk of bruising and bleeding.

Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with GRAPE

Some medications are changed and broken down by the liver. Grape might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Cyclosporine (Neoral, Sandimmune) interacts with GRAPE

Drinking purple grape juice along with cyclosporine might decrease how much cyclosporine the body absorbs. This could decrease the effects of cyclosporine. Separate doses of grape juice and cyclosporine by at least 2 hours to avoid this interaction.

Medications changed by the liver (Cytochrome P450 2D6 (CYP2D6) substrates) interacts with GRAPE

Some medications are changed and broken down by the liver. Grape might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Medications changed by the liver (Cytochrome P450 2E1 (CYP2E1) substrates) interacts with GRAPE

Some medications are changed and broken down by the liver. Grape might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Midazolam (Versed) interacts with GRAPE

Taking grape seed extract for at least one week might increase how quickly the body gets rid of midazolam. This might decrease the effects of midazolam. But taking only a single dose of grape seed extract doesn't seem to have an effect on midazolam.

Minor InteractionBe watchful with this combination Medications changed by the liver (Cytochrome P450 2C9 (CYP2C9) substrates) interacts with GRAPE Some medications are changed and broken down by the liver. Grape might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Medications changed by the liver (Cytochrome P450 2C9 (CYP2C9) substrates) interacts with GRAPE

Some medications are changed and broken down by the liver. Grape might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

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