Endocrine System and Glands of The Human Body

What Is the Endocrine System?

The endocrine system is a network of glands in your body that make the hormones that help cells talk to each other. They’re responsible for almost every cell, organ, and function in your body.

If your endocrine system isn't healthy, you might have problems developing during puberty, getting pregnant, or managing stress. You also might gain weight easily, have weak bones, or lack energy because too much sugar stays in your blood instead of moving into your cells where it's needed for energy.

What Is a Gland?

A gland is an organ that makes and puts out hormones that do a specific job in your body. Endocrine and exocrine glands release the substances they make into your bloodstream.

Endocrine System Functions

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Your endocrine system:

  • Makes hormones that control your moods, growth and development, metabolism, organs, and reproduction
  • Controls how your hormones are released
  • Sends those hormones into your bloodstream so they can travel to other body parts

Parts of the Endocrine System

Many glands make up the endocrine system. The hypothalamus, pituitary gland, and pineal gland are in your brain. The thyroid and parathyroid glands are in your neck. The thymus is between your lungs, the adrenals are on top of your kidneys, and the pancreas is behind your stomach. Your ovaries (if you're a woman) or testes (if you're a man) are in your pelvic region.

  • Hypothalamus. This organ connects your endocrine system with your nervous system. Its main job is to tell your pituitary gland to start or stop making hormones.
  • Pituitary gland. This is your endocrine system’s master gland. It uses information it gets from your brain to tell other glands in your body what to do. It makes many important hormones, including growth hormone; prolactin, which helps breastfeeding moms make milk; antidiuretic hormone(ADH) (vasopressin), which controls blood pressure and helps control body water balance through its effect on the kidney, corticotropin /ACTH: Adrenocorticotrophic hormone. which stimulates the adrenal gland to make certain hormones, thyroid- stimulating hormone (TSH), which stimulates the production and secretion of thyroid hormones, oxytocin which helps in milk ejection during breast feeding; and luteinizing hormone, which manages estrogen in women and testosterone in men.
  • Pineal gland. It makes a chemical called melatonin that helps your body get ready to go to sleep.
  • Thyroid gland. This gland makes thyroid hormone, which controls your growth and metabolism. If this gland doesn't make enough (a condition called hypothyroidism), everything happens more slowly. Your heart rate might slow down. You could get constipated. And you might gain weight. If it makes too much (hyperthyroidism), everything speeds up. Your heart might race. You could have diarrhea. And you might lose weight without trying. The thyroid gland also produces the hormone calcitonin, which may contribute to bone strength by helping calcium to be incorporated into bone.
  • Parathyroid. This is a set of four small glands behind your thyroid. They play a role in bone health. The glands control your levels of calcium and phosphorus.
  • Thymus. This gland makes white blood cells called T-lymphocytes that fight infection and are crucial as a child's immune system develops. The thymus starts to shrink after puberty.
  • Adrenals. Best known for making the "fight or flight" hormone adrenaline (also called epinephrine), these two glands also make hormones called corticosteroids. They affect your metabolism heart rate, oxygen intake, blood flow, and sexual function, among other things.
  • Pancreas. This organ is part of both your digestive and endocrine systems. It makes digestive enzymes that break down food. It also makes the hormones insulin and sugar' target='_blank' rel='noopener noreferrer' >glucagon. These ensure you have the right amount of sugar in your bloodstream and your cells.
  • If you don't make insulin, which is the case for people with type 1 diabetes, your blood sugar levels can get dangerously high. In type 2 diabetes, the pancreas usually makes some insulin but not enough.
  • Ovaries. In women, these organs make estrogen and progesterone. These hormones help develop breasts at puberty, regulate the menstrual cycle, and support a pregnancy.
  • Testes. In men, the testes make testosterone. It helps them grow facial and body hair at puberty. It also tells the penis to grow larger and plays a role in making sperm.

Health Issues

As you get older, it's natural to notice some things related to your endocrine system. Your metabolism tends to slow down. So you might gain weight even though you haven't changed how you eat or exercise. Hormonal shifts also explain, at least in part, why you're more likely to have heart disease, osteoporosis, and type 2 diabetes as you age.

No matter how old you are, stress, infections, and being around certain chemicals can also mess with parts of your endocrine system. And genetics or lifestyle habits can increase your chances of an endocrine disorder like hypothyroidism, diabetes, or osteoporosis.

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