BITTER ORANGE - Uses, Side Effects, and More

Medications for depression (MAOIs) interacts with BITTER ORANGE

Bitter orange contains chemicals that stimulate the body. Some medications used for depression can increase these chemicals. Taking bitter orange with these medications might cause serious side effects including very fast heartbeat and very high blood pressure. Some common MAOIs include phenelzine (Nardil), selegiline (Zelapar), and tranylcypromine (Parnate).

Midazolam (Versed) interacts with BITTER ORANGE

Bitter orange can decrease how quickly the body breaks down midazolam. Taking bitter orange along with midazolam might increase the effects and side effects of midazolam.

Caffeine interacts with BITTER ORANGE

Bitter orange is a stimulant. Caffeine is also a stimulant. Taking these products together can increase blood pressure and cause the heart to beat rapidly. This can cause serious adverse effects such as heart attack and stroke.

Dextromethorphan (Robitussin DM, and others) interacts with BITTER ORANGE

Bitter orange might decrease how quickly the liver breaks down dextromethorphan. Taking bitter orange along with dextromethorphan might increase the effects and side effects of dextromethorphan such as nervousness, drowsiness, and others.

Felodipine (Plendil) interacts with BITTER ORANGE

The liver breaks down felodipine to get rid of it. Bitter orange might decrease how quickly the liver gets rid of felodipine. Taking bitter orange along with felodipine might increase the effects and side effects of felodipine.

Indinavir (Crixivan) interacts with BITTER ORANGE

The liver breaks down indinavir to get rid of it. Bitter orange might decrease how quickly the liver breaks down indinavir. Taking bitter orange along with indinavir might increase the effects and side effects of indinavir.

Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with BITTER ORANGE

Some medications are changed and broken down by the liver. Bitter orange might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Medications that can cause an irregular heartbeat (QT interval-prolonging drugs) interacts with BITTER ORANGE

Bitter orange might affect electrical currents in the heart. This can increase the risk of having an irregular heartbeat. Some medications can have this same effect. Taking bitter orange with these medications might increase the risk for a serious heart issue.

Stimulant drugs interacts with BITTER ORANGE

Stimulants, such as amphetamines and cocaine, speed up the nervous system. By speeding up the nervous system, stimulant medications can increase blood pressure and speed up the heartbeat. Bitter orange might also speed up the nervous system. Taking bitter orange along with stimulant drugs might cause serious problems including increased heart rate and high blood pressure.

Medications for diabetes (Antidiabetes drugs) interacts with BITTER ORANGE

Bitter orange might lower blood sugar levels. Taking bitter orange along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.

Colchicine interacts with BITTER ORANGE

Bitter orange might affect levels of colchicine. Using colchicine with bitter orange may reduce the benefits or increase the side effects of colchicine.

Sildenafil (Viagra) interacts with BITTER ORANGE

The body breaks down sildenafil to get rid of it. Bitter orange can decrease how quickly the body breaks down sildenafil. Taking bitter orange along with sildenafil might increase the effects and side effects of sildenafil.

Minor InteractionBe watchful with this combination Medications changed by the liver (Cytochrome P450 2D6 (CYP2D6) substrates) interacts with BITTER ORANGE Some medications are changed and broken down by the liver. Bitter orange might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Medications changed by the liver (Cytochrome P450 2D6 (CYP2D6) substrates) interacts with BITTER ORANGE

Some medications are changed and broken down by the liver. Bitter orange might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

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