ADENOSINE - Uses, Side Effects, and More

Dipyridamole (Persantine) interacts with ADENOSINE

The body breaks down adenosine to get rid of it. Dipyridamole (Persantine) can decrease the break down of adenosine. Decreasing the breakdown of adenosine can cause heart problems. Do not take adenosine if you are taking dipyridamole (Persantine).

Carbamazepine (Tegretol) interacts with ADENOSINE

Adenosine can slow down the heartbeat. Taking carbamazepine (Tegretol) with adenosine might cause the heart to beat too slowly. Do not take adenosine if you are taking carbamazepine (Tegretol).

Medications for gout (Antigout drugs) interacts with ADENOSINE

Gout is caused by a build-up of uric acid crystals in the joints. Adenosine can increase uric acid in the body and might reduce the effectiveness of medications for gout. Some medications for gout include allopurinol (Zyloprim), colchicine, probenecid (Benemid), and others.

Methylxanthines interacts with ADENOSINE

Methylxanthines might block the effects of adenosine. Adenosine is often used by doctors to do a test on the heart. This test is called a cardiac stress test. Stop drinking black tea or other caffeine containing products at least 24 hours before a cardiac stress test. Methylxanthines include aminophylline, caffeine, and theophylline.

  • For a heart condition marked by episodes of rapid heart rate (paroxysmal supraventricular tachycardia): Healthcare providers give adenosine by IV. A dose of 6 mg is given over 1-2 seconds. If this is not effective within 1-2 minutes, 12 mg can be given and repeated once if necessary.
  • For involuntary weight loss in people who are very ill (cachexia or wasting syndrome): Healthcare providers give ATP by IV at a dose of up to 75 mcg/kg per minute over 30 hours. This dose is given every 2-4 weeks for up to 28 weeks.

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