GRAPEFRUIT - Uses, Side Effects, and More

Artemether (Artenam, Paluther) interacts with GRAPEFRUIT

Grapefruit juice can decrease how quickly the body breaks down artemether. Drinking grapefruit juice while taking artemether might increase the effects and side effects of artemether. Do not drink grapefruit juice if you are taking artemether.

Buspirone (BuSpar) interacts with GRAPEFRUIT

Grapefruit juice might increase how much buspirone the body absorbs. Drinking grapefruit juice while taking buspirone might increase the effects and side effects of buspirone.

Carbamazepine (Tegretol) interacts with GRAPEFRUIT

Grapefruit juice might increase how much carbamazepine the body absorbs. Drinking grapefruit juice while taking carbamazepine might increase the effects and side effects of carbamazepine.

Carvedilol (Coreg) interacts with GRAPEFRUIT

Grapefruit juice seems to decrease how quickly the body breaks down carvedilol. Drinking grapefruit juice while taking carvedilol might increase the effects and side effects of carvedilol.

Cisapride (Propulsid) interacts with GRAPEFRUIT

Grapefruit juice might decrease how quickly the body gets rid of cisapride. Drinking grapefruit juice while taking cisapride might increase the effects and side effects of cisapride.

Clomipramine (Anafranil) interacts with GRAPEFRUIT

Grapefruit juice might decrease how quickly the body gets rid of clomipramine. Taking grapefruit juice along with clomipramine might increase the effects and side effects of clomipramine.

Cyclosporine (Neoral, Sandimmune) interacts with GRAPEFRUIT

Grapefruit might increase how much cyclosporine the body absorbs. Drinking grapefruit juice while taking cyclosporine might increase the side effects of cyclosporine.

Dextromethorphan (Robitussin DM, and others) interacts with GRAPEFRUIT

Grapefruit might decrease how quickly the body gets rid of dextromethorphan. Drinking grapefruit juice while taking dextromethorphan might increase the effects and side effects of dextromethorphan.

Estrogens interacts with GRAPEFRUIT

Grapefruit juice seems to decrease how quickly the body breaks down estrogens and increase how much estrogen the body absorbs. Drinking grapefruit juice while taking estrogens might increase estrogen levels and side effects associated with estrogen.

Etoposide (VePesid) interacts with GRAPEFRUIT

Grapefruit might decrease how much etoposide the body absorbs. Drinking grapefruit juice while taking etoposide might decrease the effects of etoposide. Separate taking this medication from consuming grapefruit by at least 4 hours.

Medications for high blood pressure (Calcium channel blockers) interacts with GRAPEFRUIT

Grapefruit juice might increase how much medication for high blood pressure the body absorbs. Drinking grapefruit juice while taking some medications for high blood pressure might cause your blood pressure to go too low.

Methylprednisolone interacts with GRAPEFRUIT

Grapefruit juice can decrease how quickly the body gets rid of methylprednisolone. Drinking grapefruit juice while taking methylprednisolone might increase the effects and side effects of methylprednisolone.

Praziquantel (Biltricide) interacts with GRAPEFRUIT

Grapefruit juice can decrease how quickly the body breaks down praziquantel. Drinking grapefruit juice while taking praziquantel might increase the effects and side effects of praziquantel.

Quinidine interacts with GRAPEFRUIT

Grapefruit juice might decrease how fast the body gets rid of quinidine. Drinking grapefruit juice while taking quinidine might increase the chance of side effects from quinidine.

Scopolamine (Transderm Scop) interacts with GRAPEFRUIT

Grapefruit juice can decrease how fast the body breaks down scopolamine. Drinking grapefruit juice while taking scopolamine might increase the effects and side effects of scopolamine.

Sedative medications (Benzodiazepines) interacts with GRAPEFRUIT

Sedative medications can cause sleepiness and drowsiness. Drinking grapefruit juice while taking some sedative medications can increase the effects and side effects of some sedative medications.

Sildenafil (Viagra) interacts with GRAPEFRUIT

Grapefruit can decrease how quickly the body breaks down sildenafil. Drinking grapefruit juice while taking sildenafil can increase the effects and side effects of sildenafil.

Terfenadine (Seldane) interacts with GRAPEFRUIT

Grapefruit can increase how much terfenadine the body absorbs. Drinking grapefruit juice while taking terfenadine might increase the effects and side effects of terfenadine.

Amiodarone (Cordarone) interacts with GRAPEFRUIT

Grapefruit juice can increase how much amiodarone the body absorbs. Drinking grapefruit juice might increase the effects and side effects of amiodarone. Avoid drinking grapefruit juice if you are taking amiodarone.

Methadone (Dolophine) interacts with GRAPEFRUIT

Grapefruit juice can decrease how quickly the body breaks down methadone. Drinking grapefruit juice while taking methadone can increase the effects and side effects of methadone.

Halofantrine interacts with GRAPEFRUIT

Grapefruit juice seems to decrease how quickly the body breaks down halofantrine. Drinking grapefruit juice while taking halofantrine might increase halofantrine levels and side effects associated with halofantrine, including abnormal heartbeat.

Tacrolimus (Prograf) interacts with GRAPEFRUIT

Grapefruit can decrease how quickly the body breaks down tacrolimus. Eating grapefruit or drinking grapefruit juice while taking tacrolimus can increase the effects and side effects of tacrolimus. Avoid eating grapefruit or drinking grapefruit juice if you are taking tacrolimus.

Celiprolol (Celicard) interacts with GRAPEFRUIT

Grapefruit appears to decrease how much celiprolol is absorbed by the body. This might decrease the effects of celiprolol. Separate administration of celiprolol and consumption of grapefruit by at least 4 hours.

Clopidogrel (Plavix) interacts with GRAPEFRUIT

Clopidogrel needs to be activated by the body to work. Grapefruit appears to decrease how much clopidogrel is activated by the body. This might reduce the effects of clopidogrel.

Ticagrelor (Brilinta) interacts with GRAPEFRUIT

Grapefruit can decrease how quickly the body breaks down ticagrelor. Drinking grapefruit juice while taking ticagrelor can increase the effects and side effects of ticagrelor.

Medications used for lowering cholesterol (Statins) interacts with GRAPEFRUIT

Grapefruit juice might decrease how quickly the body breaks down some "statin" medications. Drinking grapefruit juice while taking certain "statins" might increase the effects and side effects of these medications.

Medications that can cause an irregular heartbeat (QT interval-prolonging drugs) interacts with GRAPEFRUIT

Grapefruit might affect electrical currents in the heart. This can increase the risk of having an irregular heartbeat. Some medications can have this same effect. Taking grapefruit with these medications might increase the risk for a serious heart issue.

Caffeine interacts with GRAPEFRUIT

Grapefruit might decease how quickly the body gets rid of caffeine. Drinking grapefruit juice while taking caffeine might increase the side effects of caffeine including jitteriness, headache, and a fast heartbeat.

Erythromycin interacts with GRAPEFRUIT

Grapefruit can decrease how quickly the body gets rid of erythromycin. Taking grapefruit juice along with erythromycin might increase the effects and side effects of erythromycin.

Fexofenadine (Allegra) interacts with GRAPEFRUIT

Grapefruit might decrease how much fexofenadine the body absorbs. Drinking grapefruit juice while taking fexofenadine might decrease the effects of fexofenadine. Separate taking this medication from consuming grapefruit by at least 4 hours.

Itraconazole (Sporanox) interacts with GRAPEFRUIT

Grapefruit juice might change how much itraconazole the body absorbs. But there isn't enough information to know if this interaction is a major concern.

Losartan (Cozaar) interacts with GRAPEFRUIT

The liver activates losartan to make it work. Grapefruit juice might decrease how quickly the body activates losartan. Drinking grapefruit juice while taking losartan might decrease the effects of losartan.

Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates) interacts with GRAPEFRUIT

Some medications are changed and broken down by the liver. Grapefruit might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Medications changed by the liver (Cytochrome P450 2C19 (CYP2C19) substrates) interacts with GRAPEFRUIT

Some medications are changed and broken down by the liver. Grapefruit might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Medications changed by the liver (Cytochrome P450 2C9 (CYP2C9) substrates) interacts with GRAPEFRUIT

Some medications are changed and broken down by the liver. Grapefruit might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Saquinavir (Fortovase, Invirase) interacts with GRAPEFRUIT

Drinking grapefruit juice can increase how much saquinavir the body absorbs. Drinking grapefruit juice while taking saquinavir might increase the effects and side effects of saquinavir.

Theophylline interacts with GRAPEFRUIT

Drinking grapefruit juice might decrease the effects of theophylline. There's not enough information to know if this is a big concern.

Warfarin (Coumadin) interacts with GRAPEFRUIT

Warfarin is used to slow blood clotting. Drinking grapefruit juice might increase the effects of warfarin and increase the chances of bruising and bleeding. Be sure to have your blood checked regularly. The dose of your warfarin might need to be changed.

Aliskiren (Tekturna, Rasilez) interacts with GRAPEFRUIT

Aliskiren is moved by pumps in cells in the body. Grapefruit might change how these pumps work, making this medication less effective. Separate taking this medication from consuming grapefruit by at least 4 hours.

Fluvoxamine (Luvox) interacts with GRAPEFRUIT

Grapefruit juice can increase how much fluvoxamine the body absorbs. Drinking grapefruit juice while taking fluvoxamine might increase the effects and side effects of fluvoxamine.

Levothyroxine (Synthroid, others) interacts with GRAPEFRUIT

Levothyroxine is moved by pumps in cells in the body. Grapefruit might change how these pumps work, making this medication less effective. Separate taking this medication from consuming grapefruit by at least 4 hours.

Nilotinib (Tasigna) interacts with GRAPEFRUIT

Grapefruit juice can increase how much nilotinib the body absorbs. Drinking grapefruit juice while taking nilotinib might increase the effects and side effects.

Pitavastatin (Livalo) interacts with GRAPEFRUIT

Grapefruit juice might decrease how quickly the body breaks down pitavastatin. Drinking grapefruit juice while taking pitavastatin might increase the effects and side effects of pitavastatin.

Primaquine interacts with GRAPEFRUIT

Grapefruit juice can increase how much primaquine is available in the body. But it's not clear if this is a big concern or what effects it might have.

Sertraline (Zoloft) interacts with GRAPEFRUIT

Grapefruit can decrease how quickly the body breaks down sertraline. Drinking grapefruit juice while taking sertraline can increase the effects and side effects of sertraline.

Talinolol interacts with GRAPEFRUIT

Grapefruit juice can reduce how much talinolol is available in the body. Drinking grapefruit juice with talinolol might reduce the effects of talinolol.

Budesonide (Entocort, UCERIS) interacts with GRAPEFRUIT

Grapefruit might decease how quickly the body gets rid of budesonide. Drinking grapefruit while taking budesonide might increase the side effects of budesonide.

Colchicine interacts with GRAPEFRUIT

Grapefruit might decrease how quickly the body gets rid of colchicine. Taking grapefruit juice along with colchicine might increase the effects and side effects of colchicine.

Nadolol (Corgard) interacts with GRAPEFRUIT

Nadolol is moved by pumps in cells in the body. Grapefruit might change how these pumps work. But it's not clear if this is a big concern. Until more is known, follow any instructions on the nadolol label related to intake of grapefruit.

Oxycodone (Oxycontin) interacts with GRAPEFRUIT

Grapefruit juice can decrease how quickly the body breaks down oxycodone. Drinking grapefruit juice while taking oxycodone might increase the side effects of oxycodone.

Sunitinib (Sutent) interacts with GRAPEFRUIT

Grapefruit might decrease how quickly the body breaks down sunitinib. Drinking grapefruit juice while taking sunitinib might increase the effects and side effects of sunitinib. Until more is known, follow any instructions on the sunitinib label related to intake of grapefruit.

Tolvaptan (Samsca) interacts with GRAPEFRUIT

Grapefruit can decrease how quickly the body breaks down tolvaptan. Drinking grapefruit juice while taking tolvaptan can increase the effects and side effects of tolvaptan.

Dapoxetine (Priligy) interacts with GRAPEFRUIT

Grapefruit juice can decrease how quickly the body gets rid of dapoxetine. Taking grapefruit juice along with dapoxetine might increase the effects and side effects of dapoxetine.

Prasugrel (Effient) interacts with GRAPEFRUIT

Prasugrel needs to be activated by the body to work. Grapefruit appears to decrease how much prasugrel is activated by the body. This might reduce the effects of prasugrel.

Tadalafil (Cialis) interacts with GRAPEFRUIT

Grapefruit juice might decrease how quickly the body breaks down tadalafil. Drinking grapefruit juice while taking tadalafil might increase the effects and side effects of tadalafil.

Acebutolol (Sectral) interacts with GRAPEFRUIT

Acebutolol is moved by pumps in cells in the body. Grapefruit might change how these pumps work, making this medication less effective. Separate taking this medication from consuming grapefruit by at least 4 hours.

Amprenavir (Agenerase) interacts with GRAPEFRUIT

Grapefruit might slightly decrease how much amprenavir is absorbed by the body. But this interaction is probably not a major concern.

Medications moved by pumps in cells (P-glycoprotein substrates) interacts with GRAPEFRUIT

Some medications are moved in and out of cells by pumps. Grapefruit might change how these pumps work and change how much medication stays in the body. In some cases, this might change the effects and side effects of a medication.

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