GOLDENSEAL - Uses, Side Effects, and More

Digoxin (Lanoxin) interacts with GOLDENSEAL

Taking goldenseal with digoxin might cause slight increases in digoxin levels in the body. If you take digoxin, talk to your healthcare provider before taking goldenseal.

Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with GOLDENSEAL

Some medications are changed and broken down by the liver. Goldenseal might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Medications moved by pumps in cells (P-Glycoprotein Substrates) interacts with GOLDENSEAL

Some medications are moved in and out of cells by pumps. Goldenseal might change how these pumps work and change how much medication stays in the body. In some cases, this might change the effects and side effects of a medication.

Dextromethorphan (Robitussin DM, and others) interacts with GOLDENSEAL

Goldenseal contains berberine, which might decrease how quickly the body breaks down dextromethorphan. Taking goldenseal while taking dextromethorphan might increase the effects and side effects of dextromethorphan.

Losartan (Cozaar) interacts with GOLDENSEAL

Goldenseal contains berberine, which might change how quickly the body breaks down losartan. Taking goldenseal while taking losartan might change the effects of losartan.

Medications changed by the liver (Cytochrome P450 2C9 (CYP2C9) substrates) interacts with GOLDENSEAL

Some medications are changed and broken down by the liver. Goldenseal might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Medications changed by the liver (Cytochrome P450 2E1 (CYP2E1) substrates) interacts with GOLDENSEAL

Some medications are changed and broken down by the liver. Goldenseal might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Medications for diabetes (Antidiabetes drugs) interacts with GOLDENSEAL

Goldenseal might lower blood sugar levels. Taking goldeneal along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.

Medications for high blood pressure (Antihypertensive drugs) interacts with GOLDENSEAL

Goldenseal might lower blood pressure. Taking goldenseal along with medications that lower blood pressure might cause blood pressure to go too low. Monitor your blood pressure closely.

Sedative medications (CNS depressants) interacts with GOLDENSEAL

Goldenseal might cause sleepiness and slowed breathing. Some medications, called sedatives, can also cause sleepiness and slowed breathing. Taking goldenseal with sedative medications might cause breathing problems and/or too much sleepiness.

Tacrolimus (Prograf) interacts with GOLDENSEAL

Goldenseal contains berberine, which might decrease how quickly the body breaks down tacrolimus. Taking goldenseal with tacrolimus might increase the effects and side effects of tacrolimus.

Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with GOLDENSEAL

Goldenseal might slow blood clotting. Taking goldenseal along with medications that also slow blood clotting might increase the risk of bruising and bleeding.

Metformin (Glucophage) interacts with GOLDENSEAL

Goldenseal might decrease the amount of metformin in the body. Taking goldenseal with metformin might decrease the effects of metformin.

Oseltamivir interacts with GOLDENSEAL

Taking goldenseal with oseltamivir might prevent oseltamivir from being converted to its active form. However, it is not clear if this interaction is serious enough to reduce the effects of oseltamivir.

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