CANNABIS - Uses, Side Effects, and More

Sedative medications (CNS depressants) interacts with CANNABIS

Cannabis might cause sleepiness and slowed breathing. Some medications, called sedatives, can also cause sleepiness and slowed breathing. Taking cannabis with sedative medications might cause breathing problems and/or too much sleepiness.

Theophylline interacts with CANNABIS

Taking cannabis might decrease the effects of theophylline. But there isn't enough information to know if this is a big concern.

Warfarin (Coumadin) interacts with CANNABIS

Using cannabis might increase the effects of warfarin. Smoking cannabis while taking warfarin might increase the chance of bruising and bleeding.

Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with CANNABIS

Cannabis might slow blood clotting. Taking cannabis along with medications that also slow blood clotting might increase the risk of bruising and bleeding.

Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with CANNABIS

Some medications are changed and broken down by the liver. Cannabis might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Medications moved by pumps in cells (P-glycoprotein Substrates) interacts with CANNABIS

Some medications are moved in and out of cells by pumps. Cannabis might change how these pumps work and change how much medication stays in the body. In some cases, this might change the effects and side effects of a medication.

Anesthesia interacts with CANNABIS

Using cannabis might increase how much anesthesia your doctor needs to give to you for surgery. Tell your doctor if you regularly use cannabis. If possible, stop using cannabis at least 2 weeks before surgery.

Medications for dissolving blood clots (Thrombolytic drugs) interacts with CANNABIS

Cannabis might slow blood clotting. Taking cannabis with medications used for dissolving blood clots might increase the chance of bleeding and bruising.

Medications changed by the liver (Cytochrome P450 2C9 (CYP2C9) substrates) interacts with CANNABIS

Some medications are changed and broken down by the liver. Cannabis might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Medications that increase breakdown of other medications by the liver (Cytochrome P450 3A4 (CYP3A4) inducers) interacts with CANNABIS

Cannabis is changed and broken down by the liver. Some drugs increase how quickly the liver changes and breaks down cannabis. This could change the effects and side effects of cannabis.

Medications that decrease the breakdown of other medications in the liver (Cytochrome P450 3A4 (CYP3A4) inhibitors) interacts with CANNABIS

Cannabis is changed and broken down by the liver. Some drugs decrease how quickly the liver changes and breaks down cannabis. This could change the effects and side effects of cannabis.

Alcohol interacts with CANNABIS

Using cannabis with alcohol might increase the effects of alcohol on the central nervous system. This might increase the risk for some side effects, such as drowsiness and mood changes.

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